Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | DUT | P33316 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30168643 | 0.79 | DPP4 (0.38) | CA12CA1CA2CA9CA14 | |
| SCHEMBL2374116 | 0.74 | CA12 (0.33) | CA12CA1CA2CA9CA14 | |
| SCHEMBL5203599 | 0.74 | MAPK1 (0.36) | CA12CA1CA2CA9CA14 | |
| SCHEMBL30926426 | 0.74 | CA12 (0.39) | CA12CA1CA2CA9CA14 | |
| SCHEMBL18442831 | 0.74 | CA12 (0.39) | CA12CA1CA2CA9CA14 | |
| SCHEMBL25259391 | 0.73 | CA12 (0.35) | CA12CA1CA2CA9CA14 | |
| SCHEMBL1727175 | 0.73 | KDM4E (0.34) | CA12CA1CA2CA9CA14 | |
| SCHEMBL30168622 | 0.73 | CA12 (0.35) | CA12CA1CA2CA9CA14 | |
| SCHEMBL24789635 | 0.73 | CA12 (0.35) | CA12CA1CA2CA9CA14 | |
| SCHEMBL23273052 | 0.71 | CA12 (0.38) | CA12CA1CA2CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022266069-A1 | TRICYCLIC KRAS G12D INHIBITORS | ERASCA, INC. (US) | 2022-12-22 | — | — | WO | disclosed |