SCHEMBL30168728

CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(N)=O)NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)C(C)C)C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 5)

	gene	UniProt	supporting neighbours	confidence
▸	TFPI	P10646	1/20	0.58

▸	F2	P00734	2/20	0.56

▸	GLP1R	P43220	4/20	0.52

▸	VIPR2	P41587	3/20	0.52

▸	VIPR1	P32241	2/20	0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29836289	0.97	TFPI (0.58)	TFPIF2GLP1RVIPR2VIPR1
SCHEMBL30168703	0.96	TFPI (0.59)	TFPIF2GLP1RVIPR1
SCHEMBL30168717	0.95	F2 (0.55)	TFPIF2
SCHEMBL30168761	0.93	F2 (0.58)	TFPIF2GLP1R
SCHEMBL29836420	0.93	TFPI (0.59)	TFPIF2GLP1RVIPR1
SCHEMBL29836469	0.92	F2 (0.56)	TFPIF2
SCHEMBL30168722	0.90	TFPI (0.59)	TFPIF2VIPR2VIPR1
SCHEMBL30844087	0.90	TFPI (0.57)	TFPIF2GLP1RVIPR2VIPR1
SCHEMBL29836357	0.90	F2 (0.59)	TFPIF2GLP1R
SCHEMBL31415943	0.89	BACE1 (0.54)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-12428638-B2	Three-component CRISPR/Cas complex system and uses thereof	THE JACKSON LABORATORY (US)	2025-09-30	—	—	US	disclosed
US-20230071712-A1	THREE-COMPONENT CRISPR/CAS COMPLEX SYSTEM AND USES THEREOF	THE JACKSON LABORATORY (US)	2023-03-09	—	—	US	disclosed