SCHEMBL30168795

SCHEMBL30168795

CN(C(=O)c1cccc(Cl)c1)[C@@H]1CCC[C@H](C(=O)NN)C1

nearest known ligand 0.57

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GPR142 Q7Z601 10/20 0.57
GRM5 P41594 8/20 0.47
HSD11B1 P28845 1/20 0.45
HSD11B2 P80365 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19797904 1.00 GPR142 (0.57) GPR142GRM5HSD11B1HSD11B2
SCHEMBL19797905 1.00 GPR142 (0.57) GPR142GRM5HSD11B1HSD11B2
SCHEMBL30168803 1.00 GPR142 (0.57) GPR142GRM5HSD11B1HSD11B2
SCHEMBL30168796 1.00 GPR142 (0.57) GPR142GRM5HSD11B1HSD11B2
SCHEMBL19797895 1.00 GPR142 (0.57) GPR142GRM5HSD11B1HSD11B2
SCHEMBL23716713 0.86 GPR142 (0.54) GPR142GRM5HSD11B1HSD11B2
SCHEMBL17020126 0.86 GPR142 (0.54) GPR142GRM5HSD11B1HSD11B2
SCHEMBL30168800 0.85 GPR142 (0.54) GPR142GRM5HSD11B1HSD11B2
SCHEMBL17008877 0.85 GPR142 (0.54) GPR142GRM5HSD11B1HSD11B2
SCHEMBL19797892 0.85 GPR142 (0.54) GPR142GRM5HSD11B1HSD11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109715609-B Cyclohexylbenzamide compounds 伊莱利利公司 2023-01-10 CN disclosed