Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | METAP1 | P53582 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30169368 | 0.86 | GAA (0.50) | GAAALOX15TSHRMEN1KMT2A | |
| SCHEMBL30334596 | 0.83 | SMN1; SMN2 (0.46) | GAAALOX15TSHRMEN1KMT2A | |
| SCHEMBL14293758 | 0.83 | POLB (0.47) | METAP1MAPT | |
| SCHEMBL30169573 | 0.81 | GAA (0.46) | GAAALOX15TSHRMETAP1MEN1 | |
| SCHEMBL30169382 | 0.81 | GAA (0.46) | GAAALOX15TSHRMETAP1MEN1 | |
| SCHEMBL30169501 | 0.81 | GAA (0.46) | GAAALOX15TSHRMETAP1MEN1 | |
| SCHEMBL30169605 | 0.81 | GAA (0.46) | GAAALOX15TSHRMETAP1MEN1 | |
| SCHEMBL13700974 | 0.72 | KMT2A (0.65) | GAATSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL14469497 | 0.71 | POLB (0.46) | DRD2DRD4DRD3MAPT | |
| SCHEMBL17271375 | 0.71 | GAA (0.86) | GAAALOX15TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115551593-A | Compounds and methods for modulating splicing | 雷密克斯医疗公司 | 2022-12-30 | — | — | CN | disclosed |