Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PLAT | P00750 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30169508 | 0.86 | GAA (0.51) | GAAALOX15MEN1KMT2AATM | |
| SCHEMBL30169382 | 0.85 | GAA (0.46) | GAAALOX15MEN1KMT2AATM | |
| SCHEMBL30169573 | 0.85 | GAA (0.46) | GAAALOX15MEN1KMT2AATM | |
| SCHEMBL30169605 | 0.85 | GAA (0.46) | GAAALOX15MEN1KMT2AATM | |
| SCHEMBL30169501 | 0.85 | GAA (0.46) | GAAALOX15MEN1KMT2AATM | |
| SCHEMBL12893949 | 0.82 | TP53 (0.59) | TP53POLB | |
| SCHEMBL13319463 | 0.82 | CYP11B2 (0.50) | GAAMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL30169404 | 0.81 | NPC1 (0.44) | GAAALOX15ALDH1A1HTTNPC1 | |
| SCHEMBL30327130 | 0.81 | POLB (0.42) | GAAALOX15MEN1KMT2ATSHR | |
| SCHEMBL30334639 | 0.75 | POLB (0.40) | GAAALDH1A1LMNAPOLBCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115551593-A | Compounds and methods for modulating splicing | 雷密克斯医疗公司 | 2022-12-30 | — | — | CN | disclosed |