Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.38 |
| ▸ | KDM1A | O60341 | 3/20 | 0.36 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16954130 | 1.00 | NOTUM (0.41) | NOTUMHTR2CALDH1A1MAPK1OPRL1 | |
| SCHEMBL31223122 | 0.87 | HTR2C (0.58) | HTR2CSLC6A4 | |
| SCHEMBL31222914 | 0.87 | OPRL1 (0.43) | NOTUMHTR2CALDH1A1MAPK1OPRL1 | |
| SCHEMBL28506474 | 0.85 | QDPR (0.40) | OPRL1HTT | |
| SCHEMBL23857836 | 0.83 | HTR2C (0.38) | HTR2CALDH1A1MAPK1SLC6A4HPGD | |
| SCHEMBL29186352 | 0.81 | OPRL1 (0.42) | OPRL1 | |
| SCHEMBL30767882 | 0.81 | OPRL1 (0.42) | OPRL1 | |
| SCHEMBL10925090 | 0.80 | SLC6A4 (0.31) | ALDH1A1MAPK1KDM1AKDM1BSLC6A4 | |
| SCHEMBL16905177 | 0.79 | PTGDR (0.40) | HTR2CMAPK1KDM1AKDM1BSLC6A4 | |
| SCHEMBL15822058 | 0.79 | MEN1 (0.36) | NOTUMMAPK1KDM1AKDM1BSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4126825-A1 | AMINOCYCLOBUTANES AS MONOACYLGLYCEROL LIPASE MODULATORS | Janssen Pharmaceutica NV (BE) | 2023-02-08 | — | — | EP | disclosed |