SCHEMBL30169852

SCHEMBL30169852

NCCCC[C@H](NC(=O)CNC(=O)C(=O)C1CCCN1C(=O)CNC(=O)c1ccnc2ccccc12)C(=O)O

nearest known ligand 0.86

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FAP Q12884 20/20 0.86

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30570389 0.91 FAP (0.85) FAP
SCHEMBL25239463 0.91 FAP (0.86) FAP
SCHEMBL23888303 0.88 FAP (0.86) FAP
SCHEMBL23888302 0.88 FAP (0.86) FAP
SCHEMBL25237898 0.86 FAP (1.00) FAP
SCHEMBL30169744 0.86 FAP (1.00) FAP
SCHEMBL25282265 0.86 FAP (1.00) FAP
SCHEMBL30415358 0.83 FAP (0.93) FAP
SCHEMBL26349050 0.83 FAP (0.83) FAP
SCHEMBL30169782 0.83 FAP (1.00) FAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4126841-A1 COMPOUNDS FOR INHIBITION OF FIBROBLAST ACTIVATION PROTEIN Ustav Organicke Chemie A Biochemie Av Cr, V.v.i. (CZ) 2023-02-08 EP disclosed