Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 11/20 | 0.55 |
| ▸ | ARG2 | P78540 | 11/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL894070 | 1.00 | ARG1 (0.55) | ARG1ARG2MAPTGAACYP2C9 | |
| Hydrochloric Acid SCHEMBL895716 | 0.99 | ARG1 (0.54) | ARG1ARG2MAPTGAACYP2C9 | |
| SCHEMBL20683476 | 0.90 | MAPT (0.52) | MAPTGAACYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL894848 | 0.89 | ARG1 (0.62) | ARG1ARG2 | |
| SCHEMBL30169977 | 0.89 | ARG1 (0.62) | ARG1ARG2 | |
| SCHEMBL30169855 | 0.82 | ARG1 (0.62) | ARG1ARG2MAPTSMN1; SMN2LMNA | |
| SCHEMBL894946 | 0.82 | ARG1 (0.62) | ARG1ARG2MAPTSMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL895133 | 0.81 | ARG1 (0.61) | ARG1ARG2MAPTSMN1; SMN2LMNA | |
| SCHEMBL894693 | 0.80 | ARG1 (0.59) | ARG1ARG2 | |
| SCHEMBL30170065 | 0.80 | ARG1 (0.59) | ARG1ARG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283332-A1 | USES OF ARGINASE INHIBITORS FOR MANAGING KIDNEY DISEASE AND CARDIOVASCULAR CONDITIONS | EMORY UNIVERSITY (US) | 2023-01-12 | — | — | WO | disclosed |