SCHEMBL30169898

SCHEMBL30169898

NC(CCCCB(O)O)(CCCN1Cc2ccccc2C1)C(=O)O

nearest known ligand 0.90

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ARG1 P05089 19/20 0.90
ARG2 P78540 17/20 0.90

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14879593 1.00 ARG1 (0.90) ARG1ARG2
SCHEMBL14879635 0.95 ARG1 (1.00) ARG1ARG2
SCHEMBL14879636 0.95 ARG1 (1.00) ARG1ARG2
SCHEMBL30169870 0.95 ARG1 (1.00) ARG1ARG2
SCHEMBL10006144 0.93 ARG1 (0.92) ARG1ARG2
SCHEMBL29657477 0.93 ARG1 (0.92) ARG1ARG2
SCHEMBL29657628 0.91 ARG1 (0.92) ARG1ARG2
SCHEMBL10006186 0.91 ARG1 (0.92) ARG1ARG2
SCHEMBL895005 0.88 ARG1 (1.00) ARG1ARG2
SCHEMBL30169876 0.88 ARG1 (1.00) ARG1ARG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023283332-A1 USES OF ARGINASE INHIBITORS FOR MANAGING KIDNEY DISEASE AND CARDIOVASCULAR CONDITIONS EMORY UNIVERSITY (US) 2023-01-12 WO disclosed