Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 16/20 | 0.80 |
| ▸ | ARG2 | P78540 | 16/20 | 0.80 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL895490 | 1.00 | ARG1 (0.80) | ARG1ARG2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL894259 | 0.89 | ARG1 (1.00) | ARG1ARG2TP53MAPT | |
| SCHEMBL20683443 | 0.89 | ARG1 (0.63) | ARG1ARG2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL12292192 | 0.89 | ARG1 (0.64) | ARG1ARG2LMNATP53MAPT | |
| Hydrochloric Acid SCHEMBL894561 | 0.88 | ARG1 (0.98) | ARG1ARG2TP53MAPT | |
| SCHEMBL12293026 | 0.88 | ARG1 (0.63) | ARG1ARG2LMNATP53MAPT | |
| SCHEMBL894098 | 0.83 | ARG1 (0.89) | ARG1ARG2NPC1RAB9ALMNA | |
| SCHEMBL894099 | 0.83 | ARG1 (0.89) | ARG1ARG2NPC1RAB9ALMNA | |
| SCHEMBL894063 | 0.83 | ARG1 (0.67) | ARG1ARG2MEN1KMT2A | |
| SCHEMBL19055915 | 0.83 | ARG1 (0.64) | ARG1ARG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283332-A1 | USES OF ARGINASE INHIBITORS FOR MANAGING KIDNEY DISEASE AND CARDIOVASCULAR CONDITIONS | EMORY UNIVERSITY (US) | 2023-01-12 | — | — | WO | disclosed |