SCHEMBL30169954

SCHEMBL30169954

N[C@](CCCCB(O)O)(C(=O)O)C1CC(NCc2ccc3c(c2)Cc2ccccc2-3)C1

nearest known ligand 0.50

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ ARG1 P05089 20/20 0.50
▸ ARG2 P78540 20/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16240601 1.00 ARG1 (0.50) ARG1ARG2
SCHEMBL14897573 1.00 ARG1 (0.50) ARG1ARG2
SCHEMBL16240599 1.00 ARG1 (0.50) ARG1ARG2
SCHEMBL18323837 0.90 ARG1 (0.38) ARG1ARG2
SCHEMBL16241497 0.86 ARG1 (0.54) ARG1ARG2
SCHEMBL16240648 0.86 ARG1 (0.54) ARG1ARG2
SCHEMBL14897400 0.86 ARG1 (0.54) ARG1ARG2
SCHEMBL2564628 0.85 ARG1 (0.64) ARG1ARG2
SCHEMBL2564626 0.85 ARG1 (0.64) ARG1ARG2
SCHEMBL19055992 0.85 ARG1 (0.64) ARG1ARG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023283332-A1 USES OF ARGINASE INHIBITORS FOR MANAGING KIDNEY DISEASE AND CARDIOVASCULAR CONDITIONS EMORY UNIVERSITY (US) 2023-01-12 — — WO disclosed
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