Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 3/20 | 0.55 |
| ▸ | CSF1R | P07333 | 7/20 | 0.52 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.48 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.48 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 3/20 | 0.47 |
| ▸ | KIT | P10721 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL524596 | 1.00 | AR (0.55) | ARCSF1RNTRK1NTRK3NTRK2 | |
| SCHEMBL3490042 | 0.87 | MAOB (0.57) | ARMAOB | |
| SCHEMBL23949942 | 0.86 | MAOB (0.46) | ARMAOBMAOAAPP | |
| SCHEMBL8156292 | 0.86 | APP (0.53) | ARCSF1RMAOBMAOAAPP | |
| SCHEMBL23882866 | 0.86 | APP (0.53) | ARCSF1RMAOBMAOAAPP | |
| SCHEMBL7145572 | 0.82 | CA12 (0.61) | CSF1RNTRK1NTRK3NTRK2MAOB | |
| SCHEMBL2276512 | 0.82 | MAOB (0.68) | MAOBMAOAAPP | |
| SCHEMBL28838736 | 0.82 | MRGPRX4 (0.57) | ARMAOBMAOAAPP | |
| SCHEMBL7378373 | 0.82 | TUBB1 (0.48) | CSF1RMAOBMAOAAPP | |
| SCHEMBL23235862 | 0.82 | AR (0.55) | ARCSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115697989-A | Tropomyosin Receptor Kinase (TRK) degrading compounds and methods of use | 上海睿跃生物科技有限公司 | 2023-02-03 | — | — | CN | disclosed |
| EP-4110772-A1 | TROPOMYOSIN RECEPTOR KINASE (TRK) DEGRADATION COMPOUNDS AND METHODS OF USE | Cullgen (Shanghai), Inc. (CN) | 2023-01-04 | — | — | EP | disclosed |