Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.48 |
| ▸ | CCR5 | P51681 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CSF1R | P07333 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7383657 | 0.88 | CCNB2 (0.47) | CCR5RAB9ANPC1TDP1CSF1R | |
| SCHEMBL7383659 | 0.88 | CCNB2 (0.47) | CCR5RAB9ANPC1TDP1CSF1R | |
| SCHEMBL26473036 | 0.87 | TUBB1 (0.48) | TUBB1CCR5RAB9ANPC1TDP1 | |
| SCHEMBL21347524 | 0.85 | TUBB1 (0.59) | TUBB1CCR5RAB9ANPC1TDP1 | |
| SCHEMBL6325013 | 0.84 | MAOB (0.54) | CCR5RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL7147744 | 0.84 | TUBB1 (0.66) | TUBB1CCR5RAB9ANPC1TDP1 | |
| SCHEMBL524596 | 0.82 | AR (0.55) | CSF1RMAOBMAOAAPP | |
| SCHEMBL30170765 | 0.82 | AR (0.55) | CSF1RMAOBMAOAAPP | |
| SCHEMBL5286017 | 0.81 | ALDH1A1 (0.56) | TUBB1CCR5RAB9ANPC1TDP1 | |
| SCHEMBL5631282 | 0.80 | TUBB1 (0.51) | TUBB1CCR5RAB9ANPC1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200405-A1 | BENZENAMINE DERIVATIVES AS ANTI-COAGULANTS | BERLEX LABORATORIES, INC. (US) | 2002-05-02 | — | — | EP | disclosed |
| US-6350761-B1 | INHIBITORS OF THE ENZYME, FACTOR XA; | BERLEX LABORATORIES, INC. | 2002-02-26 | — | — | US | disclosed |
| WO-2001009093-A1 | BENZENAMINE DERIVATIVES AS ANTI-COAGULANTS | BERLEX LABORATORIES, INC. (US) | 2001-02-08 | — | — | WO | disclosed |