Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.36 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIK4 | Q16099 | 1/20 | 0.36 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1341445 | 0.98 | MEN1 (0.39) | MEN1KMT2AGRIN2DGRIN3BLMNA | |
| SCHEMBL28719374 | 0.96 | MEN1 (0.38) | MEN1KMT2AGRIN2DGRIN3BLMNA | |
| SCHEMBL29828520 | 0.80 | SYK (0.37) | SYKALDH1A1TDP1JUNNFKB1 | |
| SCHEMBL22647296 | 0.80 | SYK (0.37) | SYKALDH1A1TDP1JUNNFKB1 | |
| SCHEMBL15120617 | 0.80 | SYK (0.37) | SYKTDP1JUNNFKB1NFKB2 | |
| SCHEMBL17194940 | 0.78 | SYK (0.39) | MEN1KMT2ALMNASYKALDH1A1 | |
| SCHEMBL15689372 | 0.78 | SYK (0.50) | MEN1KMT2ALMNASYKALDH1A1 | |
| Lithium Ion SCHEMBL22288327 | 0.77 | SYK (0.35) | SYKTDP1JUNNFKB1NFKB2 | |
| SCHEMBL474100 | 0.77 | ALDH1A1 (0.46) | MEN1KMT2ASYKALDH1A1TDP1 | |
| Lithium Ion SCHEMBL30079578 | 0.77 | SYK (0.35) | SYKTDP1JUNNFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114650990-B | Heterocyclic compounds for inhibiting TYK2 activity | 北京诺诚健华医药科技有限公司 | 2023-02-03 | — | — | CN | disclosed |