SCHEMBL30171482

SCHEMBL30171482

O=C(c1cnc2c(ccc3ccccc32)c1O)C(F)(F)F

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.47
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
MEN1 O00255 1/20 0.47
LDHA P00338 1/20 0.44
MAPT P10636 2/20 0.43
TP53 P04637 1/20 0.43
PLA2G2D Q9UNK4 1/20 0.43
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42
HPGD P15428 1/20 0.42
CYP1B1 Q16678 5/20 0.42
P2RX1 P51575 1/20 0.40
P2RX3 P56373 1/20 0.40
P2RX4 Q99571 1/20 0.40
P2RX7 Q99572 1/20 0.40
MAPK1 P28482 1/20 0.40
POLB P06746 1/20 0.40
RAD52 P43351 1/20 0.40
CNR2 P34972 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11705770 0.82 KMT2A (0.52) KMT2ANPC1RAB9AMEN1LDHA
SCHEMBL6149991 0.77 MAPK1 (0.45) KMT2AMEN1MAPTKDM4EALDH1A1
SCHEMBL30171496 0.72 ATM (0.41) KMT2ANPC1RAB9AMEN1KDM4E
SCHEMBL8875203 0.72 KMT2A (0.50) KMT2ANPC1RAB9AMEN1LDHA
SCHEMBL30171444 0.71 LDHA (0.38) KMT2ALDHAPLA2G2DKDM4EMAPK1
SCHEMBL29645052 0.71 PLA2G2D (0.63) KMT2ANPC1RAB9AMEN1MAPT
SCHEMBL1827963 0.71 PLA2G2D (0.63) KMT2ANPC1RAB9AMEN1MAPT
SCHEMBL30171486 0.71 PLA2G2D (0.41) KMT2APLA2G2DKDM4EMAPK1CNR2
SCHEMBL18573220 0.71 KMT2A (0.66) KMT2ANPC1RAB9AMEN1LDHA
SCHEMBL29946522 0.67 ABCG2 (0.50) KMT2AMEN1LDHAMAPTPLA2G2D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250074925-A1 RARE EARTH COMPLEX SAGAMI CHEMICAL RESEARCH INSTITUTE (JP) 2025-03-06 US disclosed
EP-4365180-A1 RARE EARTH COMPLEX Tosoh Corporation (JP) 2024-05-08 EP disclosed
WO-2023282236-A1 RARE EARTH COMPLEX 東ソー株式会社 2023-01-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250074925-A1 RARE EARTH COMPLEX L1CAM, CHRM1, NPM1 KMT2A 3223/4885NPC1 1197/4885RAB9A 2697/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.