Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PHGDH | O43175 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27656391 | 0.86 | LMNA (0.49) | LMNAKDM4EADRB2ADRB1ADRB3 | |
| SCHEMBL27676391 | 0.86 | LMNA (0.49) | LMNAKDM4EADRB2ADRB1ADRB3 | |
| SCHEMBL27741919 | 0.80 | LMNA (0.55) | LMNAKDM4EADRB2ADRB1ADRB3 | |
| SCHEMBL964905 | 0.80 | LMNA (0.55) | LMNAKDM4EADRB2ADRB1ADRB3 | |
| SCHEMBL27676393 | 0.77 | LMNA (0.52) | LMNAKDM4EADRB2ADRB1ADRB3 | |
| SCHEMBL27656400 | 0.77 | LMNA (0.52) | LMNAKDM4EADRB2ADRB1ADRB3 | |
| SCHEMBL301530 | 0.77 | — | — | |
| SCHEMBL5262347 | 0.76 | LMNA (0.52) | LMNAKDM4EADRB2ADRB1ADRB3 | |
| SCHEMBL28003757 | 0.76 | LMNA (0.58) | LMNAKDM4EADRB2ADRB1ADRB3 | |
| SCHEMBL860309 | 0.76 | F7 (0.58) | LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4850702-B2 | — | — | 2012-01-11 | — | — | JP | claimed |