Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | PANK3 | Q9H999 | 4/20 | 0.53 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21771104 | 0.93 | RAB9A (0.62) | MAPTALDH1A1KMT2AHSD17B10SMN1; SMN2 | |
| SCHEMBL31504200 | 0.88 | PANK3 (0.60) | MAPTKMT2ASMN1; SMN2MEN1RAB9A | |
| SCHEMBL22495457 | 0.88 | PANK3 (0.60) | MAPTKMT2ASMN1; SMN2MEN1RAB9A | |
| SCHEMBL22495428 | 0.88 | PANK3 (0.54) | MAPTALDH1A1KMT2AHSD17B10SMN1; SMN2 | |
| SCHEMBL30172136 | 0.88 | PANK3 (0.54) | MAPTALDH1A1KMT2AHSD17B10SMN1; SMN2 | |
| SCHEMBL22495414 | 0.87 | KMT2A (0.53) | MAPTALDH1A1KMT2AHSD17B10SMN1; SMN2 | |
| SCHEMBL31504191 | 0.87 | KMT2A (0.53) | MAPTALDH1A1KMT2AHSD17B10SMN1; SMN2 | |
| SCHEMBL22495234 | 0.85 | PANK3 (0.57) | MAPTALDH1A1KMT2AHSD17B10SMN1; SMN2 | |
| SCHEMBL22495294 | 0.85 | KMT2A (0.51) | MAPTALDH1A1KMT2AHSD17B10SMN1; SMN2 | |
| SCHEMBL31504202 | 0.85 | MAPT (0.54) | MAPTALDH1A1KMT2AHSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3728234-B1 | RADIOLABELED COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2025-05-14 | — | — | EP | disclosed |
| US-11541132-B2 | Radiolabeled compounds | HOFFMANN-LA ROCHE INC. (US) | 2023-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11541132-B2 | Radiolabeled compounds | SNCA, APP, BACE1 | MAPT 16/4885ALDH1A1 1769/4885KMT2A 4463/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.