Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 2/20 | 0.73 |
| ▸ | CCR1 | P32246 | 8/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CCR3 | P51677 | 7/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | CCR2 | P41597 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1949177 | 1.00 | ABCB11 (0.73) | ABCB11CCR1LMNACCR3KCNH2 | |
| SCHEMBL1950911 | 1.00 | ABCB11 (0.73) | ABCB11CCR1LMNACCR3KCNH2 | |
| SCHEMBL1950910 | 1.00 | ABCB11 (0.73) | ABCB11CCR1LMNACCR3KCNH2 | |
| SCHEMBL1683051 | 1.00 | ABCB11 (0.73) | ABCB11CCR1LMNACCR3KCNH2 | |
| SCHEMBL2016861 | 1.00 | ABCB11 (0.73) | ABCB11CCR1LMNACCR3KCNH2 | |
| SCHEMBL3813054 | 0.95 | ABCB11 (0.81) | ABCB11CCR1LMNACCR3KCNH2 | |
| SCHEMBL3813060 | 0.95 | ABCB11 (0.81) | ABCB11CCR1LMNACCR3KCNH2 | |
| SCHEMBL3813533 | 0.95 | ABCB11 (0.81) | ABCB11CCR1LMNACCR3KCNH2 | |
| SCHEMBL3809872 | 0.91 | ABCB11 (0.73) | ABCB11CCR1LMNACCR3KCNH2 | |
| SCHEMBL3809868 | 0.91 | ABCB11 (0.73) | ABCB11CCR1LMNACCR3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4115885-A1 | A PHARMACEUTICAL COMPOSITION COMPRISING BAY 86-5277 AND SALTS THEREOF FOR USE IN THE TREATMENT OF VIRAL INFECTIONS AND HYPERINFLAMMATION | Charité - Universitätsmedizin Berlin (DE) | 2023-01-11 | — | — | EP | disclosed |