Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.62 |
| ▸ | HRH1 | P35367 | 4/20 | 0.50 |
| ▸ | CCR3 | P51677 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | BACE1 | P56817 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | ATF4 | P18848 | 2/20 | 0.43 |
| ▸ | CCR5 | P51681 | 3/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5141124 | 0.88 | ABCB11 (0.55) | ABCB11HRH1CCR3LMNAMEN1 | |
| SCHEMBL3149898 | 0.86 | ABCB11 (0.63) | ABCB11HRH1CCR3LMNAMEN1 | |
| SCHEMBL3149904 | 0.86 | ABCB11 (0.63) | ABCB11HRH1CCR3LMNAMEN1 | |
| SCHEMBL3145540 | 0.85 | ABCB11 (0.61) | ABCB11HRH1CCR3LMNAMEN1 | |
| SCHEMBL3145527 | 0.85 | ABCB11 (0.61) | ABCB11HRH1CCR3LMNAMEN1 | |
| SCHEMBL1683017 | 0.82 | ABCB11 (0.83) | ABCB11HRH1CCR3LMNAMEN1 | |
| Trifluoroacetic Acid SCHEMBL3145177 | 0.82 | ABCB11 (0.57) | ABCB11HRH1CCR3LMNAMEN1 | |
| Trifluoroacetic Acid SCHEMBL3150378 | 0.81 | ABCB11 (0.57) | ABCB11HRH1CCR3LMNAMEN1 | |
| SCHEMBL1682980 | 0.81 | ABCB11 (0.74) | ABCB11HRH1CCR3LMNAMEN1 | |
| SCHEMBL3048644 | 0.80 | ABCB11 (0.60) | ABCB11HRH1CCR3LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4115885-A1 | A PHARMACEUTICAL COMPOSITION COMPRISING BAY 86-5277 AND SALTS THEREOF FOR USE IN THE TREATMENT OF VIRAL INFECTIONS AND HYPERINFLAMMATION | Charité - Universitätsmedizin Berlin (DE) | 2023-01-11 | — | — | EP | disclosed |