Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.55 |
| ▸ | NTRK1 | P04629 | 16/20 | 0.39 |
| ▸ | JAK2 | O60674 | 15/20 | 0.37 |
| ▸ | JAK3 | P52333 | 2/20 | 0.37 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30172440 | 0.85 | AAK1 (0.55) | AAK1NTRK1JAK2JAK3PTK2 | |
| SCHEMBL30172435 | 0.81 | AAK1 (0.51) | AAK1NTRK1JAK2JAK3PTK2 | |
| SCHEMBL30172469 | 0.78 | AAK1 (0.61) | AAK1NTRK1JAK2JAK3PTK2 | |
| SCHEMBL30172445 | 0.78 | AAK1 (0.60) | AAK1NTRK1JAK2JAK3PTK2 | |
| SCHEMBL30172451 | 0.75 | AAK1 (0.54) | AAK1NTRK1JAK2JAK3PTK2 | |
| Hydrochloric Acid SCHEMBL30172441 | 0.74 | AAK1 (0.53) | AAK1NTRK1JAK2JAK3PTK2 | |
| SCHEMBL17099734 | 0.74 | AAK1 (0.55) | AAK1NTRK1JAK2JAK3PTK2 | |
| SCHEMBL19467027 | 0.73 | AAK1 (0.83) | AAK1NTRK1JAK2JAK3PTK2 | |
| SCHEMBL30172404 | 0.72 | AAK1 (0.53) | AAK1NTRK1JAK2JAK3PTK2 | |
| SCHEMBL15261668 | 0.72 | AAK1 (0.57) | AAK1NTRK1JAK2JAK3PTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115677705-A | AAK1 inhibitor and application thereof | 武汉人福创新药物研发中心有限公司 | 2023-02-03 | — | — | CN | disclosed |