Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17204517 | 1.00 | NAPRT (0.49) | NAPRTCYP1A2CYP3A4CYP2C9RECQL | |
| SCHEMBL17204516 | 1.00 | NAPRT (0.49) | NAPRTCYP1A2CYP3A4CYP2C9RECQL | |
| SCHEMBL17168992 | 0.83 | CYP19A1 (0.42) | KMT2ANPSR1GAAALDH1A1CYP19A1 | |
| SCHEMBL8949899 | 0.83 | MAPT (0.47) | KMT2ATSHRNPSR1ALDH1A1MAPK1 | |
| SCHEMBL8949906 | 0.83 | MAPT (0.47) | KMT2ATSHRNPSR1ALDH1A1MAPK1 | |
| SCHEMBL701469 | 0.78 | NAPRT (0.59) | NAPRTCYP1A2CYP3A4CYP2C9KMT2A | |
| SCHEMBL30225124 | 0.78 | NAPRT (0.59) | NAPRTCYP1A2CYP3A4CYP2C9KMT2A | |
| SCHEMBL7916715 | 0.78 | F7 (0.50) | KMT2APOLBGAAALDH1A1LMNA | |
| SCHEMBL6629937 | 0.78 | F7 (0.50) | KMT2APOLBGAAALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL30543987 | 0.77 | NAPRT (0.57) | NAPRTCYP1A2CYP3A4CYP2C9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111620870-B | Compound and application thereof in expansion of hematopoietic stem cells and/or hematopoietic progenitor cells | 蒙特利尔大学 | 2023-01-03 | — | — | CN | disclosed |