Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 1/20 | 0.50 |
| ▸ | F3 | P13726 | 1/20 | 0.50 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.50 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.50 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.50 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.50 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.50 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6629937 | 1.00 | F7 (0.50) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL30930819 | 0.84 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1MAPTTBXAS1TP53 | |
| SCHEMBL2422440 | 0.84 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1MAPTTBXAS1TP53 | |
| SCHEMBL15765091 | 0.84 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1MAPTTBXAS1TP53 | |
| SCHEMBL2422438 | 0.84 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1MAPTTBXAS1TP53 | |
| SCHEMBL29105669 | 0.84 | ALDH1A1 (0.58) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL6947971 | 0.84 | ALDH1A1 (0.58) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL29882651 | 0.84 | ALDH1A1 (0.58) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL6947970 | 0.84 | ALDH1A1 (0.58) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL2891426 | 0.82 | KMT2A (0.44) | ALDH1A1MAPTKMT2ALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258829-B1 | ANTIARRTHMIA AGENTS AND CARDIOVASCULAR DISORDERS | TOA EIYO LTD. (JP) | 2001-07-10 | — | — | US | disclosed |
| EP-0972767-A1 | CYCLOALKA[b]PYRIDINE-3-CARBONYLGUANIDINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND DRUGS CONTAINING THE SAME | TOA EIYO LTD. (JP) | 2000-01-19 | — | — | EP | disclosed |