Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23638268 | 1.00 | MAPT (0.43) | MAPTUSP2MAPK1NPC1RAB9A | |
| SCHEMBL4777935 | 0.87 | MAPT (0.45) | MAPTUSP2MAPK1NPC1RAB9A | |
| SCHEMBL30698370 | 0.87 | MAPT (0.45) | MAPTUSP2MAPK1NPC1RAB9A | |
| SCHEMBL24815631 | 0.86 | ALDH1A1 (0.41) | MAPTUSP2MAPK1NPC1RAB9A | |
| SCHEMBL15111986 | 0.86 | PPARG (0.46) | MAPTUSP2MAPK1NPC1RAB9A | |
| SCHEMBL17673776 | 0.84 | MAPT (0.43) | MAPTUSP2MAPK1NPC1RAB9A | |
| SCHEMBL24816122 | 0.83 | NPC1 (0.47) | MAPTNPC1RAB9AHDAC6NTRK1 | |
| SCHEMBL31588703 | 0.82 | MAPT (0.46) | MAPTUSP2MAPK1NPC1RAB9A | |
| SCHEMBL31473684 | 0.82 | MAPT (0.46) | MAPTUSP2MAPK1NPC1RAB9A | |
| SCHEMBL15111868 | 0.82 | MAPT (0.46) | MAPTUSP2MAPK1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118724899-A | 2 (1H) -quinoxalinone compounds, pharmaceutical compositions and uses thereof | 中国药科大学 | 2024-10-01 | — | — | CN | disclosed |
| CN-115504980-A | Pyrimido nitrogen-containing six-membered aromatic heterocyclic compound and application thereof | 石药集团中奇制药技术（石家庄）有限公司 | 2022-12-23 | — | — | CN | disclosed |