Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 12/20 | 0.55 |
| ▸ | JAK2 | O60674 | 10/20 | 0.55 |
| ▸ | JAK3 | P52333 | 6/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.41 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28597935 | 1.00 | JAK1 (0.55) | JAK1JAK2JAK3ADRA2AHPGDS | |
| SCHEMBL28598975 | 0.79 | JAK1 (0.60) | JAK1JAK2JAK3HPGDS | |
| SCHEMBL30173342 | 0.79 | JAK1 (0.60) | JAK1JAK2JAK3HPGDS | |
| SCHEMBL28603790 | 0.79 | JAK1 (0.72) | JAK1JAK2JAK3HPGDS | |
| SCHEMBL30173268 | 0.79 | JAK1 (0.72) | JAK1JAK2JAK3HPGDS | |
| SCHEMBL30173314 | 0.78 | JAK1 (0.56) | JAK1JAK2JAK3HPGDS | |
| SCHEMBL28598686 | 0.78 | JAK1 (0.56) | JAK1JAK2JAK3HPGDS | |
| SCHEMBL30173271 | 0.76 | ADRA2A (0.47) | ADRA2AMKNK1PRKCQPRKCDNPC1 | |
| SCHEMBL28596888 | 0.76 | ADRA2A (0.47) | ADRA2AMKNK1PRKCQPRKCDNPC1 | |
| SCHEMBL28919002 | 0.76 | JAK2 (0.72) | JAK1JAK2JAK3HPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113200983-B | Compound with pyrrolopyridine structure, preparation method and medical application | 中国药科大学 | 2023-01-03 | — | — | CN | disclosed |