Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 14/20 | 0.50 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24055262 | 1.00 | RIPK1 (0.50) | RIPK1HTR1AFAAHNR1H2NR1H3 | |
| SCHEMBL25240594 | 1.00 | RIPK1 (0.50) | RIPK1HTR1AFAAHNR1H2NR1H3 | |
| SCHEMBL24055292 | 0.92 | RIPK1 (0.52) | RIPK1FAAH | |
| SCHEMBL24055273 | 0.92 | RIPK1 (0.52) | RIPK1FAAH | |
| SCHEMBL24055463 | 0.91 | RIPK1 (0.49) | RIPK1FAAH | |
| SCHEMBL24055263 | 0.91 | RIPK1 (0.50) | RIPK1HTR1A | |
| SCHEMBL25274375 | 0.91 | RIPK1 (0.50) | RIPK1HTR1A | |
| SCHEMBL24055264 | 0.90 | RIPK1 (0.48) | RIPK1FAAH | |
| SCHEMBL25279638 | 0.90 | RIPK1 (0.48) | RIPK1 | |
| SCHEMBL24056134 | 0.90 | RIPK1 (0.48) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115697972-B | Receptor-interacting protein 1 inhibitors including piperazine heterocyclic amide urea | 维泰瑞隆有限公司 | 2024-11-22 | — | — | CN | disclosed |
| CN-115697972-A | Receptor-interacting protein 1 inhibitors comprising piperazine heterocyclic amide ureas | 维泰瑞隆有限公司 | 2023-02-03 | — | — | CN | disclosed |