SCHEMBL30173672

SCHEMBL30173672

CSc1nccc(C=N[S@@+]([O-])C(C)(C)C)n1

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
KMT2A Q03164 1/20 0.37
NPSR1 Q6W5P4 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28974173 1.00 MEN1 (0.37) MEN1NPC1RAB9AKMT2ANPSR1
SCHEMBL23985441 1.00 MEN1 (0.37) MEN1NPC1RAB9AKMT2ANPSR1
SCHEMBL26194412 1.00 MEN1 (0.37) MEN1NPC1RAB9AKMT2ANPSR1
SCHEMBL28974175 1.00 MEN1 (0.37) MEN1NPC1RAB9AKMT2ANPSR1
SCHEMBL29989648 0.77 IDH1 (0.34)
SCHEMBL29162016 0.77 IDH1 (0.34)
SCHEMBL29162014 0.77 IDH1 (0.34)
SCHEMBL28836041 0.73 L3MBTL1 (0.55) MEN1NPC1RAB9AKMT2ANPSR1
SCHEMBL23985444 0.73 MEN1 (0.43) MEN1NPC1RAB9AKMT2ANPSR1
SCHEMBL15874008 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115867348-B Imidazopyrimidines as IL-17 modulators 詹森药业有限公司 2025-05-06 CN disclosed
CN-115867348-A Imidazopyrimidines as IL-17 modulators 詹森药业有限公司 2023-03-28 CN disclosed
EP-4143193-A1 IMIDAZOPYRIMIDINES AS MODULATORS OF IL-17 JANSSEN Pharmaceutica NV (BE) 2023-03-08 EP disclosed