Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.40 |
| ▸ | IDO1 | P14902 | 7/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28264057 | 0.83 | LMNA (0.43) | LMNATP53HTTCRHR1CYP19A1 | |
| SCHEMBL20888260 | 0.82 | MDM2 (0.40) | CRHR1AOC3 | |
| SCHEMBL21147867 | 0.78 | CYP2C9 (0.57) | LMNATP53HTTCYP19A1CYP2C9 | |
| SCHEMBL18827495 | 0.78 | CYP19A1 (0.64) | LMNATP53HTTCYP19A1CYP2C9 | |
| SCHEMBL23347771 | 0.77 | TP53 (0.44) | LMNATP53HTTCRHR1CYP19A1 | |
| SCHEMBL23347704 | 0.77 | NISCH (0.42) | LMNACYP3A4IDO1TDO2CYP1A2 | |
| SCHEMBL16212082 | 0.76 | TP53 (0.55) | LMNATP53HTTCYP19A1CYP2C9 | |
| SCHEMBL18568287 | 0.76 | LMNA (0.43) | LMNATP53HTTIDO1TDO2 | |
| SCHEMBL18682098 | 0.75 | HTT (0.46) | LMNATP53HTTCRHR1IDO1 | |
| SCHEMBL17069233 | 0.75 | HTT (0.46) | LMNATP53HTTCRHR1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115515426-A | Active compound combinations and fungicide compositions comprising them | 拜耳公司 | 2022-12-23 | — | — | CN | disclosed |