Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 6/20 | 0.38 |
| ▸ | PDE4A | P27815 | 5/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.38 |
| ▸ | KMO | O15229 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 2/20 | 0.36 |
| ▸ | GRN | P28799 | 1/20 | 0.35 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23782388 | 1.00 | NPC1 (0.41) | NPC1LMNAPOLBRAB9APTGDR2 | |
| SCHEMBL23791891 | 0.90 | NPC1 (0.40) | NPC1LMNAPOLBRAB9APTGDR2 | |
| SCHEMBL23782532 | 0.86 | POLB (0.42) | NPC1LMNAPOLBRAB9APTGDR2 | |
| SCHEMBL23792330 | 0.86 | NPC1 (0.43) | NPC1LMNAPOLBRAB9APTGDR2 | |
| SCHEMBL26240299 | 0.85 | GRN (0.40) | NPC1LMNAPOLBRAB9APTGDR2 | |
| SCHEMBL23792015 | 0.84 | GRN (0.40) | NPC1LMNAPOLBRAB9APTGDR2 | |
| SCHEMBL23792710 | 0.84 | PTGDR2 (0.44) | NPC1LMNAPOLBRAB9APTGDR2 | |
| SCHEMBL23782516 | 0.84 | TEAD2 (0.37) | NPC1LMNAPOLBRAB9APTGDR2 | |
| SCHEMBL30173731 | 0.84 | TEAD2 (0.37) | NPC1LMNAPOLBRAB9APTGDR2 | |
| SCHEMBL23791714 | 0.83 | BRAF (0.38) | NPC1LMNAPOLBRAB9APTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115515685-B | EIF4E inhibitors and uses thereof | 皮克医疗公司 | 2025-04-08 | — | — | CN | disclosed |
| CN-115515685-A | EIF4E inhibitor and application thereof | 皮克医疗公司 | 2022-12-23 | — | — | CN | disclosed |