Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 9/20 | 0.56 |
| ▸ | JAK2 | O60674 | 4/20 | 0.40 |
| ▸ | JAK1 | P23458 | 3/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | SLC27A1 | Q6PCB7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25208803 | 0.87 | TYK2 (0.47) | TYK2AHRKDM4EALDH1A1F10 | |
| SCHEMBL30367326 | 0.87 | TYK2 (0.47) | TYK2AHRKDM4EALDH1A1F10 | |
| SCHEMBL25529013 | 0.83 | TYK2 (0.46) | TYK2AHRKDM4EALDH1A1F10 | |
| SCHEMBL30367362 | 0.83 | TYK2 (0.46) | TYK2AHRKDM4EALDH1A1F10 | |
| SCHEMBL30452501 | 0.80 | TYK2 (0.47) | TYK2SLC27A1 | |
| SCHEMBL20689567 | 0.80 | TYK2 (0.47) | TYK2SLC27A1 | |
| SCHEMBL1161158 | 0.78 | TYK2 (0.50) | TYK2KDM4EALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL23071632 | 0.77 | TYK2 (0.49) | TYK2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL30174233 | 0.75 | TYK2 (0.40) | TYK2JAK2JAK1STAT3JAK3 | |
| SCHEMBL29797885 | 0.74 | TDP1 (0.44) | TYK2KDM4EALDH1A1P2RX7HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605478-A | Compounds and methods of use | 埃克塞里艾克西斯公司（US） | 2023-01-13 | — | — | CN | disclosed |