Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | GRM5 | P41594 | 4/20 | 0.34 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | SLC27A1 | Q6PCB7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20689567 | 1.00 | TYK2 (0.47) | TYK2MAPTGRM5GRM3DHFR | |
| SCHEMBL23753623 | 0.81 | NOS3 (0.39) | TYK2GRM5DHFR | |
| SCHEMBL16812410 | 0.81 | ALDH1A1 (0.37) | TYK2MAPTGRM5 | |
| SCHEMBL30174271 | 0.80 | TYK2 (0.56) | TYK2SLC27A1 | |
| SCHEMBL31572570 | 0.79 | TYK2 (0.32) | TYK2MAPT | |
| SCHEMBL20689381 | 0.78 | TYK2 (0.40) | TYK2MAPTGRM5DHFR | |
| SCHEMBL20687706 | 0.78 | TYK2 (0.54) | TYK2 | |
| SCHEMBL31563759 | 0.78 | MAPT (0.33) | TYK2MAPT | |
| SCHEMBL25208803 | 0.78 | TYK2 (0.47) | TYK2MAPTSLC27A1 | |
| SCHEMBL18161077 | 0.78 | GPR119 (0.34) | TYK2DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916207-A | Five-membered and six-membered heterocyclic compounds and application thereof as protein receptor kinase inhibitors | 轶诺(浙江)药业有限公司 | 2023-04-04 | — | — | CN | disclosed |