SCHEMBL30174476

SCHEMBL30174476

C[C@H]1CC(c2cccc(OCc3ccc4cnn(C)c4c3)n2)CCN1C(=O)OC(C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GLP1R P43220 14/20 0.40
GPR119 Q8TDV5 4/20 0.38
PRMT5 O14744 1/20 0.36
KDM2B Q8NHM5 1/20 0.36
KDM4C Q9H3R0 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24338720 1.00 GLP1R (0.40) GLP1RGPR119PRMT5KDM2BKDM4C
SCHEMBL29491404 0.89 GLP1R (0.44) GLP1RKDM2BKDM4C
SCHEMBL24338662 0.88 PRMT5 (0.47) GLP1RGPR119PRMT5
SCHEMBL30174442 0.82 GPR119 (0.49) GLP1RGPR119KDM2BKDM4C
SCHEMBL24338413 0.82 GPR119 (0.49) GLP1RGPR119KDM2BKDM4C
SCHEMBL29241286 0.82 GPR119 (0.49) GLP1RGPR119KDM2BKDM4C
SCHEMBL30732296 0.80 PDE1C (0.41) GPR119
SCHEMBL24338432 0.80 KDM2B (0.37) GPR119KDM2BKDM4C
SCHEMBL30174506 0.80 KDM2B (0.37) GPR119KDM2BKDM4C
SCHEMBL24338567 0.77 PRMT5 (0.45) GLP1RGPR119PRMT5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115515956-A Benzimidazole derivative and preparation method and medical application thereof 深圳信立泰药业股份有限公司 2022-12-23 CN disclosed