SCHEMBL30174990

SCHEMBL30174990

CC(C)C[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)Cc1c[nH]cn1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(N)=O)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 14/20 0.58
▸ NPY1R P25929 9/20 0.58
▸ NPY5R Q15761 8/20 0.58
▸ NPY2R P49146 5/20 0.58
▸ KISS1R Q969F8 4/20 0.53
▸ VIPR1 P32241 1/20 0.52
▸ VIPR2 P41587 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31388270 0.91 NPY4R (0.64) NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL30605443 0.91 NPY4R (0.54) NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL30612296 0.91 NPY4R (0.54) NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL29876127 0.91 NPY4R (0.68) NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL29875750 0.89 NPY4R (0.73) NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL29531737 0.89 NPY4R (0.51) NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL30845345 0.88 NPY4R (0.47) NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL29576266 0.88 KISS1R (0.51) NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL29609505 0.88 NPY4R (0.59) NPY4RNPY1RNPY5RNPY2R
SCHEMBL30883243 0.88 GLP1R (0.54) NPY4RNPY1RNPY5RNPY2RKISS1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230140490-A1 APTAMERS FOR USE IN THE TREATMENT OF CORONAVIRIDAE INFECTIONS Berlin Cures GmbH (DE) 2023-05-04 — — US claimed
CN-115768895-A Aptamers for the treatment of infections of the coronavirus family 柏林制药股份有限公司 2023-03-07 — — CN claimed
EP-4133083-A1 APTAMERS FOR USE IN THE TREATMENT OF CORONAVIRIDAE INFECTIONS Berlin Cures GmbH (DE) 2023-02-15 — — EP claimed
US-12606828-B2 Aptamers for use in the treatment of Coronaviridae infections APTA Therapeutics GmbH (DE) 2026-04-21 — — US disclosed
EP-4288547-B1 APTAMERS FOR USE IN THE TREATMENT OF CORONAVIRIDAE INFECTIONS Berlin Cures GmbH (DE) 2024-10-09 — — EP disclosed
US-20240191241-A1 APTAMERS FOR USE IN THE TREATMENT OF CORONAVIRIDAE INFECTIONS Berlin Cures GmbH (DE) 2024-06-13 — — US disclosed
CN-117500927-A Aptamer for treating coronaviridae infection 柏林制药股份有限公司 2024-02-02 — — CN disclosed
US-20230140490-A1 APTAMERS FOR USE IN THE TREATMENT OF CORONAVIRIDAE INFECTIONS Berlin Cures GmbH (DE) 2023-05-04 — — US disclosed
CN-115768895-A Aptamers for the treatment of infections of the coronavirus family 柏林制药股份有限公司 2023-03-07 — — CN disclosed
EP-4133083-A1 APTAMERS FOR USE IN THE TREATMENT OF CORONAVIRIDAE INFECTIONS Berlin Cures GmbH (DE) 2023-02-15 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12606828-B2 Aptamers for use in the treatment of Coronaviridae infections DNTT, TPT1, TEKT1 NPY4R 4244/4885NPY1R 2791/4885NPY5R 4424/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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