Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | DRD3 | P35462 | 3/20 | 0.38 |
| ▸ | RET | P07949 | 9/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | DRD1 | P21728 | 2/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30175296 | 0.89 | RET (0.45) | RET | |
| SCHEMBL30175294 | 0.86 | RET (0.43) | DRD2DRD3RETL3MBTL1DRD1 | |
| SCHEMBL30175367 | 0.85 | RET (0.48) | RET | |
| SCHEMBL25252185 | 0.83 | CDK2 (0.36) | DRD2DRD3RETDRD1DRD4 | |
| SCHEMBL29566683 | 0.83 | RET (0.45) | RET | |
| SCHEMBL30175370 | 0.83 | CDK2 (0.36) | DRD2DRD3RETL3MBTL1DRD1 | |
| SCHEMBL30175295 | 0.82 | RET (0.41) | RET | |
| Hydrochloric Acid SCHEMBL28993707 | 0.82 | RET (0.44) | RET | |
| SCHEMBL31044800 | 0.81 | HRH3 (0.47) | DRD2DRD3RETDRD1DRD4 | |
| SCHEMBL31298294 | 0.81 | RET (0.35) | DRD2DRD3RETDRD1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605477-B | Pyrazolo [1,5-a ] pyridine derivative, preparation method, composition and application thereof | 深圳众格生物科技有限公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-115605477-A | Pyrazolo [1,5-a ] pyridine derivative and preparation method, composition and application thereof | 深圳众格生物科技有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |