Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.36 |
| ▸ | RET | P07949 | 8/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23957695 | 1.00 | EGLN1 (0.36) | EGLN1RETALDH1A1NPC1RAB9A | |
| SCHEMBL23929889 | 0.87 | RET (0.38) | EGLN1RET | |
| SCHEMBL18821888 | 0.87 | RET (0.38) | EGLN1RET | |
| SCHEMBL28938110 | 0.87 | EGLN1 (0.37) | EGLN1P2RX3 | |
| SCHEMBL23957787 | 0.87 | RET (0.38) | EGLN1RET | |
| SCHEMBL17966632 | 0.87 | RET (0.38) | EGLN1RET | |
| SCHEMBL18806642 | 0.87 | RET (0.38) | EGLN1RET | |
| SCHEMBL23957802 | 0.87 | EGLN1 (0.37) | EGLN1P2RX3 | |
| SCHEMBL17966631 | 0.87 | RET (0.38) | EGLN1RET | |
| SCHEMBL28722963 | 0.87 | RET (0.38) | EGLN1RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605477-B | Pyrazolo [1,5-a ] pyridine derivative, preparation method, composition and application thereof | 深圳众格生物科技有限公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-115605477-A | Pyrazolo [1,5-a ] pyridine derivative and preparation method, composition and application thereof | 深圳众格生物科技有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |