Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | CCR3 | P51677 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3555629 | 0.95 | RXFP1 (0.42) | MEN1KMT2ARXFP1LMNASMN1; SMN2 | |
| SCHEMBL3562203 | 0.92 | MEN1 (0.44) | MEN1KMT2ARXFP1LMNASMN1; SMN2 | |
| SCHEMBL301630 | 0.90 | MEN1 (0.44) | MEN1KMT2ARXFP1LMNASMN1; SMN2 | |
| SCHEMBL3556044 | 0.86 | POLB (0.48) | RXFP1LMNASMN1; SMN2POLBCCR5 | |
| SCHEMBL3557526 | 0.85 | CNR1 (0.42) | LMNASMN1; SMN2POLBMAPK1TP53 | |
| SCHEMBL3560822 | 0.85 | UTS2R (0.42) | MEN1KMT2APOLBCCR5TP53 | |
| SCHEMBL3556349 | 0.85 | CCR5 (0.52) | RXFP1LMNASMN1; SMN2POLBCCR5 | |
| SCHEMBL3559074 | 0.82 | CNR1 (0.46) | LMNASMN1; SMN2POLBMAPK1TP53 | |
| SCHEMBL3560776 | 0.82 | UTS2R (0.46) | MEN1KMT2APOLBTP53MAPT | |
| SCHEMBL302944 | 0.80 | CNR1 (0.46) | LMNASMN1; SMN2POLBMAPK1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4851328-B2 | — | — | 2012-01-11 | — | — | JP | claimed |