SCHEMBL30176460

CC[C@H](C)[C@H](NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@@H](N(C)C(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CCCNC(=N)N)C(C)(C)C)[C@@H](C)CC)[C@@H](C)O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)O

nearest known ligand 0.57

Predicted protein targets (top 2)

	gene	UniProt	supporting neighbours	confidence
▸	GLP1R	P43220	18/20	0.57

▸	KEAP1	Q14145	1/20	0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30658247	0.88	KEAP1 (0.61)	GLP1RKEAP1
SCHEMBL30436863	0.87	GLP1R (0.61)	GLP1R
SCHEMBL30432968	0.87	VIPR1 (0.59)	GLP1R
SCHEMBL31603943	0.87	GLP1R (0.63)	GLP1R
SCHEMBL30576976	0.86	GLP1R (0.56)	GLP1R
SCHEMBL30495722	0.86	GLP1R (0.61)	GLP1RKEAP1
SCHEMBL30495760	0.86	KEAP1 (0.49)	GLP1RKEAP1
SCHEMBL30431379	0.86	GLP1R (0.56)	GLP1R
SCHEMBL30477260	0.85	GLP1R (0.59)	GLP1R
SCHEMBL31410890	0.85	GLP1R (0.58)	GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20230272394-A1	RNA-DIRECTED DNA CLEAVAGE BY THE Cas9-crRNA COMPLEX	VILNIUS UNIVERSITY (LT)	2023-08-31	—	—	US	disclosed
US-11555187-B2	RNA-directed DNA cleavage by the Cas9-crRNA complex	VILNIUS UNIVERSITY (LT)	2023-01-17	—	—	US	disclosed