Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.41 |
| ▸ | IMPDH2 | P12268 | 4/20 | 0.34 |
| ▸ | TYMP | P19971 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.33 |
| ▸ | KRAS | P01116 | 3/20 | 0.32 |
| ▸ | POLA1 | P09884 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NT5E | P21589 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24517731 | 1.00 | KDM4E (0.45) | KDM4ETAS1R3TAS1R1IMPDH2TYMP | |
| SCHEMBL17589376 | 0.90 | TAS1R3 (0.41) | KDM4ETAS1R3TAS1R1IMPDH2TYMP | |
| SCHEMBL24513584 | 0.90 | KDM4E (0.41) | KDM4ETAS1R3TAS1R1IMPDH2TYMP | |
| SCHEMBL20462521 | 0.87 | KDM4E (0.50) | KDM4ETAS1R3TAS1R1IMPDH2POLB | |
| SCHEMBL20462535 | 0.87 | KDM4E (0.50) | KDM4ETAS1R3TAS1R1IMPDH2POLB | |
| SCHEMBL20462537 | 0.87 | KDM4E (0.50) | KDM4ETAS1R3TAS1R1IMPDH2POLB | |
| SCHEMBL20462522 | 0.87 | KDM4E (0.50) | KDM4ETAS1R3TAS1R1IMPDH2POLB | |
| SCHEMBL20462507 | 0.87 | KDM4E (0.50) | KDM4ETAS1R3TAS1R1IMPDH2POLB | |
| SCHEMBL24517730 | 0.86 | KDM4E (0.54) | KDM4ETAS1R3TAS1R1TAAR1POLA1 | |
| SCHEMBL19954005 | 0.86 | KDM4E (0.49) | KDM4ETAS1R3TAS1R1TYMPTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4608452-A2 | PEPTIDE-ANTISENSE OLIGONUCLEOTIDES AND THEIR USE FOR TREATMENT OF NEURODEGENERATIVE DISORDERS | Eisai R&D Management Co., Ltd. (JP) | 2025-09-03 | — | — | EP | disclosed |
| US-20250092392-A1 | ANTISENSE OLIGONUCLEOTIDES AND THEIR USE FOR TREATMENT OF NEURODEGENERATIVE DISORDERS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2025-03-20 | — | — | US | disclosed |
| WO-2024092256-A2 | PEPTIDE-ANTISENSE OLIGONUCLEOTIDES AND THEIR USE FOR TREATMENT OF NEURODEGENERATIVE DISORDERS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2024-05-02 | — | — | WO | disclosed |
| EP-4330394-A2 | ANTISENSE OLIGONUCLEOTIDES AND THEIR USE FOR TREATMENT OF NEURODEGENERATIVE DISORDERS | Eisai R&D Management Co., Ltd. (JP) | 2024-03-06 | — | — | EP | disclosed |
| WO-2022232411-A2 | ANTISENSE OLIGONUCLEOTIDES AND THEIR USE FOR TREATMENT OF NEURODEGENERATIVE DISORDERS | Eisai R&D Mangement Co., Ltd. (JP) | 2022-11-03 | — | — | WO | disclosed |