SCHEMBL301782

SCHEMBL301782

C/C(C=C(C#N)C#N)=C\c1ccc(C(C)(C)C)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 10/20 0.52
KMT2A Q03164 10/20 0.52
ALDH1A1 P00352 9/20 0.52
MAPT P10636 9/20 0.52
KDM4E B2RXH2 4/20 0.52
SMN1; SMN2 Q16637 4/20 0.52
NPC1 O15118 2/20 0.52
RAB9A P51151 2/20 0.52
LMNA P02545 5/20 0.47
NPSR1 Q6W5P4 3/20 0.47
POLB P06746 1/20 0.47
CYP1A2 P05177 4/20 0.42
CISD1 Q9NZ45 2/20 0.42
THRB P10828 1/20 0.42
HPGD P15428 4/20 0.41
CYP3A4 P08684 3/20 0.41
TSHR P16473 3/20 0.41
NFKB1 P19838 3/20 0.41
BLM P54132 3/20 0.41
PMP22 Q01453 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL483410 1.00 MEN1 (0.52) MEN1KMT2AALDH1A1MAPTKDM4E
SCHEMBL12227650 0.84 KMT2A (0.68) MEN1KMT2AALDH1A1MAPTKDM4E
SCHEMBL27807205 0.80 CYP1A2 (0.48) MEN1KMT2AALDH1A1MAPTKDM4E
SCHEMBL28038607 0.80 CYP1A2 (0.48) MEN1KMT2AALDH1A1MAPTKDM4E
SCHEMBL22612509 0.73 CYP1A2 (0.50) MEN1KMT2AALDH1A1MAPTKDM4E
SCHEMBL119154 0.73 ALDH1A1 (0.59) MEN1KMT2AALDH1A1MAPTKDM4E
SCHEMBL119153 0.73 ALDH1A1 (0.59) MEN1KMT2AALDH1A1MAPTKDM4E
SCHEMBL28047896 0.72 ALDH1A1 (0.42) MEN1KMT2AALDH1A1MAPTKDM4E
SCHEMBL9637976 0.72 CYP1A2 (0.50) MEN1KMT2AALDH1A1MAPTKDM4E
SCHEMBL17285553 0.70 CYP1A2 (0.48) MEN1KMT2AALDH1A1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 651 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122016995-A Nanometer micro-plastic rapid screening method based on MALDI-TOF mass spectrum 华东理工大学 2026-05-12 CN claimed
CN-120089903-A Preparation process of amide group-based modified PIM-1 modified diaphragm for lithium sulfur battery 中国人民解放军军事科学院防化研究院 2025-06-03 CN claimed
CN-116337984-B Method for quantitatively detecting hydroxyl value of hydroxyl-terminated polybutadiene compound 青岛科技大学 2025-02-18 CN claimed
CN-119431466-A Environment-friendly synthesis method of cordycepin by taking inosine as raw material 深圳市倍昂生物科技有限公司 2025-02-14 CN claimed
CN-119416296-A Pavement structure design method based on semi-rigid base asphalt pavement fatigue damage 山东省交通科学研究院 2025-02-11 CN claimed
CN-119386685-A MOFs mixed matrix membrane for nitrogen-oxygen separation and preparation method thereof 北京理工大学 2025-02-07 CN claimed
CN-117801260-B Polymer electrolyte, electrolyte membrane, battery and preparation method thereof 上海极氪蓝色新能源技术有限公司 2024-06-25 CN claimed
CN-118195901-A Sonar image blind super-resolution method and device integrating multidimensional self-attention 武汉大学 2024-06-14 CN claimed
CN-117801260-A Polymer electrolyte, electrolyte membrane, battery and preparation method thereof 上海极氪蓝色新能源技术有限公司 2024-04-02 CN claimed
CN-117367901-A In-situ derivatization of cholesterol in tissue sections and MALDI mass spectrometry imaging method and application thereof 中国科学院大连化学物理研究所 2024-01-09 CN claimed
EP-3138623-B1 COMPOSITIONS AND PROCESSES FOR IMPROVED MASS SPECTROMETRY ANALYSIS AGENA BIOSCIENCE INC (US) 2018-08-22 EP claimed
US-20180142291-A1 COMPOSITIONS AND PROCESSES FOR IMPROVED MASS SPECTROMETRY ANALYSIS JPMORGAN CHASE BANK, N.A. 2018-05-24 US claimed
US-20180096831-A1 MATRIX-ASSISTED LASER DESORPTION MASS SPECTROMETRY OF HIGH MOLECULAR WEIGHT POLYOXYETHYLENE DERIVATIVE NOF CORPORATION (JP) 2018-04-05 US claimed
US-9873912-B2 Compositions and processes for improved mass spectrometry analysis AGENA BIOSCIENCE, INC. (US) 2018-01-23 US claimed
EP-3138623-A1 COMPOSITIONS AND PROCESSES FOR IMPROVED MASS SPECTROMETRY ANALYSIS Agena Bioscience, Inc. (US) 2017-03-08 EP claimed
US-20160319346-A1 COMPOSITIONS AND PROCESSES FOR IMPROVED MASS SPECTROMETRY ANALYSIS JPMORGAN CHASE BANK, N.A. 2016-11-03 US claimed
EP-2242561-B1 COMPOSITIONS AND PROCESSES FOR IMPROVED MASS SPECTROMETRY ANALYSIS AGENA BIOSCIENCE INC (US) 2016-08-31 EP claimed
US-20060261267-A1 Composite MALDI matrix material and methods of using it and kits thereof in MALDI AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH 2006-11-23 US claimed
WO-2006124003-A1 COMPOSITE MALDI MATRIX MATERIAL AND METHODS OF USING IT AND KITS THEREOF IN MALDI AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2006-11-23 WO claimed
US-20050158863-A1 Maldi-matrix N.V. NUTRICIA (NL) 2005-07-21 US claimed