Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 7/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 5/20 | 0.37 |
| ▸ | CTSG | P08311 | 2/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | BRS3 | P32247 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17870751 | 0.82 | GNRHR (0.44) | GNRHRCYP3A4MAPT | |
| SCHEMBL30178407 | 0.82 | GNRHR (0.44) | GNRHRCYP3A4MAPT | |
| SCHEMBL21900258 | 0.79 | APEX1 (0.42) | GNRHRCYP3A4MAPTCMA1APEX1 | |
| SCHEMBL19873689 | 0.78 | GNRHR (0.44) | GNRHRCYP3A4MEN1KMT2A | |
| SCHEMBL19873721 | 0.76 | GNRHR (0.47) | GNRHRCYP3A4 | |
| SCHEMBL30178392 | 0.76 | GNRHR (0.44) | GNRHRCYP3A4 | |
| SCHEMBL17870829 | 0.76 | GNRHR (0.42) | GNRHRCYP3A4MEN1KMT2A | |
| SCHEMBL30178400 | 0.76 | GNRHR (0.42) | GNRHRCYP3A4MEN1KMT2A | |
| SCHEMBL28663465 | 0.76 | GNRHR (0.41) | GNRHRCYP3A4MEN1KMT2A | |
| SCHEMBL19873767 | 0.75 | GNRHR (0.45) | GNRHRCYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3708566-B1 | NOVEL HETEROCYCLIC COMPOUNDS AND THE USE THEREOF IN MEDICINE AND IN COSMETICS | GALDERMA RES & DEV (FR) | 2023-02-08 | — | — | EP | disclosed |