⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25603320 | 1.00 | — | — | |
| SCHEMBL30178600 | 1.00 | — | — | |
| SCHEMBL25603329 | 1.00 | — | — | |
| SCHEMBL25603324 | 1.00 | — | — | |
| SCHEMBL30178619 | 0.87 | — | — | |
| SCHEMBL25603327 | 0.87 | — | — | |
| SCHEMBL4019567 | 0.83 | HDAC6 (0.30) | — | |
| SCHEMBL1693207 | 0.83 | HDAC6 (0.30) | — | |
| SCHEMBL1439307 | 0.83 | HDAC6 (0.30) | — | |
| SCHEMBL30178687 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023239645-A1 | SMARCA DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-12-14 | — | — | WO | disclosed |
| WO-2023278402-A1 | SMARCA DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-01-05 | — | — | WO | disclosed |