Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.46 |
| ▸ | CDK7 | P50613 | 1/20 | 0.45 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.45 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.45 |
| ▸ | GRM1 | Q13255 | 8/20 | 0.45 |
| ▸ | GRM5 | P41594 | 7/20 | 0.45 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | CDK9 | P50750 | 3/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30178737 | 0.85 | NAMPT (0.47) | CNR1NAMPTSOS1CDK7CDK13 | |
| SCHEMBL23580367 | 0.85 | NAMPT (0.47) | CNR1NAMPTSOS1CDK7CDK13 | |
| SCHEMBL30273978 | 0.83 | CNR1 (0.54) | CNR1NAMPTCDK7CDK13CDK12 | |
| SCHEMBL25036987 | 0.83 | CNR1 (0.54) | CNR1NAMPTCDK7CDK13CDK12 | |
| SCHEMBL31692148 | 0.83 | CDK9 (0.51) | CNR1NAMPTSOS1CDK7CDK13 | |
| SCHEMBL23166169 | 0.81 | CNR1 (0.52) | CNR1NAMPTSOS1CDK7CDK13 | |
| SCHEMBL29760278 | 0.81 | CNR1 (0.52) | CNR1NAMPTSOS1CDK7CDK13 | |
| SCHEMBL31017627 | 0.79 | CNR1 (0.48) | CNR1NAMPTSOS1CDK7CDK13 | |
| SCHEMBL30484043 | 0.79 | CNR1 (0.48) | CNR1NAMPTSOS1CDK7CDK13 | |
| SCHEMBL26312619 | 0.79 | NAMPT (0.52) | CNR1NAMPTSOS1CDK7CDK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023239645-A1 | SMARCA DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-12-14 | — | — | WO | disclosed |
| WO-2023278402-A1 | SMARCA DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-01-05 | — | — | WO | disclosed |