Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 2/20 | 0.45 |
| ▸ | CSF1R | P07333 | 6/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.38 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.38 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.38 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | AXL | P30530 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23999595 | 1.00 | RAF1 (0.45) | RAF1CSF1RHTR2CHTR2BPDGFRA | |
| SCHEMBL23999808 | 0.88 | MAPT (0.45) | HTR2CHTR2BPDGFRAALDH1A1GAA | |
| SCHEMBL30180568 | 0.88 | MAPT (0.45) | HTR2CHTR2BPDGFRAALDH1A1GAA | |
| SCHEMBL30180469 | 0.86 | CSF1R (0.42) | RAF1CSF1RHTR2CHTR2BALDH1A1 | |
| SCHEMBL23999621 | 0.86 | CSF1R (0.42) | RAF1CSF1RHTR2CHTR2BALDH1A1 | |
| SCHEMBL19151466 | 0.83 | MAPT (0.54) | HTR2CHTR2BPDGFRAALDH1A1GAA | |
| SCHEMBL30180527 | 0.83 | MAPT (0.54) | HTR2CHTR2BPDGFRAALDH1A1GAA | |
| SCHEMBL25825391 | 0.83 | DNMT1 (0.51) | CSF1RHTR2CHTR2BMAPTP4HTM | |
| SCHEMBL24010577 | 0.81 | DNMT1 (0.42) | CSF1RBRAFALDH1A1MAPTMAPK1 | |
| SCHEMBL30290894 | 0.81 | DNMT1 (0.42) | CSF1RBRAFALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4426279-A1 | AKT3 MODULATORS | Georgiamune Inc. (US) | 2024-09-11 | — | — | EP | disclosed |
| CN-118524833-A | AKT3 modulators | 乔治穆内公司 | 2024-08-20 | — | — | CN | disclosed |
| WO-2023081854-A1 | AKT3 MODULATORS | GEORGIAMUNE LLC (US) | 2023-05-11 | — | — | WO | disclosed |
| CN-115867562-A | AKT3 modulators | 乔治穆内有限责任公司 | 2023-03-28 | — | — | CN | disclosed |
| EP-4146667-A1 | AKT3 MODULATORS | Georgiamune LLC (US) | 2023-03-15 | — | — | EP | disclosed |