Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 2/20 | 0.42 |
| ▸ | DNMT1 | P26358 | 3/20 | 0.41 |
| ▸ | DNMT3L | Q9UJW3 | 2/20 | 0.41 |
| ▸ | DNMT3A | Q9Y6K1 | 2/20 | 0.41 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.41 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.41 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.41 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.41 |
| ▸ | RAF1 | P04049 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23999621 | 1.00 | CSF1R (0.42) | CSF1RDNMT1DNMT3LDNMT3AMYC | |
| SCHEMBL23999805 | 0.88 | KMT2A (0.47) | DNMT1DNMT3LDNMT3AMYCMAP2K3 | |
| SCHEMBL30180432 | 0.88 | KMT2A (0.47) | DNMT1DNMT3LDNMT3AMYCMAP2K3 | |
| SCHEMBL23999595 | 0.86 | RAF1 (0.45) | CSF1RDNMT1DNMT3LDNMT3AP4HTM | |
| SCHEMBL30180243 | 0.86 | RAF1 (0.45) | CSF1RDNMT1DNMT3LDNMT3AP4HTM | |
| SCHEMBL23999600 | 0.85 | DNMT1 (0.49) | DNMT1DNMT3LDNMT3AMYCMAP2K3 | |
| SCHEMBL30180539 | 0.85 | DNMT1 (0.49) | DNMT1DNMT3LDNMT3AMYCMAP2K3 | |
| SCHEMBL19151414 | 0.84 | KMT2A (0.56) | DNMT1DNMT3LDNMT3AMYCMAP2K3 | |
| SCHEMBL30180285 | 0.84 | KMT2A (0.56) | DNMT1DNMT3LDNMT3AMYCMAP2K3 | |
| SCHEMBL25825374 | 0.84 | DNMT1 (0.53) | CSF1RDNMT1DNMT3LDNMT3AMYC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4426279-A1 | AKT3 MODULATORS | Georgiamune Inc. (US) | 2024-09-11 | — | — | EP | disclosed |
| CN-118524833-A | AKT3 modulators | 乔治穆内公司 | 2024-08-20 | — | — | CN | disclosed |
| WO-2023081854-A1 | AKT3 MODULATORS | GEORGIAMUNE LLC (US) | 2023-05-11 | — | — | WO | disclosed |
| CN-115867562-A | AKT3 modulators | 乔治穆内有限责任公司 | 2023-03-28 | — | — | CN | disclosed |
| EP-4146667-A1 | AKT3 MODULATORS | Georgiamune LLC (US) | 2023-03-15 | — | — | EP | disclosed |