Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | DNMT1 | P26358 | 9/20 | 0.50 |
| ▸ | DNMT3A | Q9Y6K1 | 7/20 | 0.50 |
| ▸ | DNMT3L | Q9UJW3 | 4/20 | 0.49 |
| ▸ | EHMT1 | Q9H9B1 | 2/20 | 0.47 |
| ▸ | MYC | P01106 | 1/20 | 0.47 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.47 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.47 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAPKAPK2 | P49137 | 7/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25184667 | 1.00 | USP2 (0.51) | USP2MAPTKMT2ADNMT1DNMT3A | |
| SCHEMBL23999697 | 0.93 | KMT2A (0.44) | USP2MAPTKMT2ADNMT1DNMT3A | |
| SCHEMBL30180438 | 0.93 | KMT2A (0.44) | USP2MAPTKMT2ADNMT1DNMT3A | |
| SCHEMBL30180473 | 0.89 | MAPT (0.53) | USP2MAPTKMT2ADNMT1DNMT3A | |
| SCHEMBL23999636 | 0.89 | MAPT (0.53) | USP2MAPTKMT2ADNMT1DNMT3A | |
| SCHEMBL23999846 | 0.87 | KMT2A (0.42) | USP2MAPTKMT2ADNMT1DNMT3A | |
| SCHEMBL30180641 | 0.87 | KMT2A (0.42) | USP2MAPTKMT2ADNMT1DNMT3A | |
| SCHEMBL23999797 | 0.85 | MAPT (0.42) | USP2MAPTKMT2ADNMT1DNMT3A | |
| SCHEMBL30180612 | 0.85 | MAPT (0.42) | USP2MAPTKMT2ADNMT1DNMT3A | |
| SCHEMBL25826015 | 0.83 | DNMT1 (0.45) | USP2MAPTKMT2ADNMT1DNMT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4426279-A1 | AKT3 MODULATORS | Georgiamune Inc. (US) | 2024-09-11 | — | — | EP | disclosed |
| WO-2023081854-A1 | AKT3 MODULATORS | GEORGIAMUNE LLC (US) | 2023-05-11 | — | — | WO | disclosed |
| EP-4146667-A1 | AKT3 MODULATORS | Georgiamune LLC (US) | 2023-03-15 | — | — | EP | disclosed |