Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 8/20 | 0.45 |
| ▸ | DNMT3A | Q9Y6K1 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.42 |
| ▸ | DNMT3L | Q9UJW3 | 4/20 | 0.42 |
| ▸ | EHMT1 | Q9H9B1 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.41 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.41 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23999697 | 0.91 | KMT2A (0.44) | DNMT1DNMT3AKMT2AMEN1MAPKAPK2 | |
| SCHEMBL30180438 | 0.91 | KMT2A (0.44) | DNMT1DNMT3AKMT2AMEN1MAPKAPK2 | |
| SCHEMBL25826014 | 0.91 | MAPKAPK2 (0.47) | DNMT1DNMT3AKMT2AMEN1MAPKAPK2 | |
| SCHEMBL30180641 | 0.85 | KMT2A (0.42) | DNMT1DNMT3AKMT2AMEN1MAPKAPK2 | |
| SCHEMBL23999846 | 0.85 | KMT2A (0.42) | DNMT1DNMT3AKMT2AMEN1MAPKAPK2 | |
| SCHEMBL30180612 | 0.83 | MAPT (0.42) | DNMT1DNMT3AKMT2AMEN1MAPKAPK2 | |
| SCHEMBL23999797 | 0.83 | MAPT (0.42) | DNMT1DNMT3AKMT2AMEN1MAPKAPK2 | |
| SCHEMBL25184667 | 0.83 | USP2 (0.51) | DNMT1DNMT3AKMT2AMAPKAPK2DNMT3L | |
| SCHEMBL30180418 | 0.83 | USP2 (0.51) | DNMT1DNMT3AKMT2AMAPKAPK2DNMT3L | |
| SCHEMBL23999440 | 0.81 | MAPT (0.45) | DNMT1DNMT3AKMT2AMEN1MAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183226-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183226-A1 | AKT3 MODULATORS | AKT3, AKT2, MTOR | DNMT1 4785/4885DNMT3A 4693/4885KMT2A 3974/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.