⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3243507 | 1.00 | — | — | |
| SCHEMBL222313 | 0.77 | — | — | |
| SCHEMBL12804928 | 0.77 | — | — | |
| SCHEMBL452244 | 0.77 | — | — | |
| SCHEMBL7016006 | 0.77 | GRM5 (0.53) | — | |
| SCHEMBL29413268 | 0.77 | — | — | |
| SCHEMBL1332757 | 0.76 | HDAC8 (0.50) | — | |
| SCHEMBL31646249 | 0.76 | HDAC8 (0.50) | — | |
| Hydrochloric Acid SCHEMBL31421455 | 0.76 | GRM5 (0.51) | — | |
| SCHEMBL9947880 | 0.74 | FFAR1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118724712-A | Preparation method of organic bromine-containing compound | 郑州大学 | 2024-10-01 | — | — | CN | claimed |
| CN-118724712-A | Preparation method of organic bromine-containing compound | 郑州大学 | 2024-10-01 | — | — | CN | disclosed |
| WO-2023278759-A1 | MK2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-01-05 | — | — | WO | disclosed |