Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 7/20 | 0.63 |
| ▸ | RET | P07949 | 4/20 | 0.59 |
| ▸ | RIPK2 | O43353 | 8/20 | 0.58 |
| ▸ | ABL1 | P00519 | 6/20 | 0.57 |
| ▸ | EGFR | P00533 | 6/20 | 0.57 |
| ▸ | ABL2 | P42684 | 6/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23966729 | 1.00 | SRC (0.63) | SRCRETRIPK2ABL1EGFR | |
| SCHEMBL20351628 | 0.83 | SRC (0.80) | SRCRIPK2ABL1EGFRABL2 | |
| SCHEMBL30180698 | 0.79 | RET (0.58) | SRCRETRIPK2ABL1EGFR | |
| SCHEMBL23966914 | 0.79 | RET (0.58) | SRCRETRIPK2ABL1EGFR | |
| SCHEMBL23966913 | 0.79 | SRC (0.73) | SRCRETRIPK2ABL1EGFR | |
| SCHEMBL18044541 | 0.78 | SRC (0.81) | SRCRETRIPK2ABL1EGFR | |
| SCHEMBL23966925 | 0.78 | RIPK2 (0.72) | SRCRETRIPK2ABL1EGFR | |
| SCHEMBL28928811 | 0.78 | EGFR (0.71) | SRCRIPK2ABL1EGFRABL2 | |
| SCHEMBL28928810 | 0.78 | EGFR (0.71) | SRCRIPK2ABL1EGFRABL2 | |
| SCHEMBL23966720 | 0.77 | SRC (0.70) | SRCRETRIPK2ABL1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115843272-A | Inhibitors of NEK7 kinase | 哈利亚治疗公司 | 2023-03-24 | — | — | CN | disclosed |
| EP-4146348-A1 | INHIBITORS OF NEK7 KINASE | Halia Therapeutics, Inc. (US) | 2023-03-15 | — | — | EP | disclosed |