SCHEMBL30181036

SCHEMBL30181036

COC(=O)[C@H]1CC(C2CCC2)CN1C(=O)OC(C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 2/20 0.40
ALDH1A1 P00352 2/20 0.39
MMP2 P08253 1/20 0.39
ANPEP P15144 1/20 0.39
NR1H3 Q13133 1/20 0.39
CYP3A4 P08684 6/20 0.39
MAPT P10636 2/20 0.39
PTPN1 P18031 1/20 0.38
HSD17B10 Q99714 1/20 0.38
CHRM2 P08172 1/20 0.37
CHRM1 P11229 1/20 0.37
CHRM3 P20309 1/20 0.37
BTK Q06187 1/20 0.37
CYP1A2 P05177 1/20 0.37
POLB P06746 1/20 0.37
CYP2C19 P33261 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.36
NPC1 O15118 1/20 0.36
FKBP1A P62942 1/20 0.36
KDM4E B2RXH2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29523552 0.97 ALDH1A1 (0.42) NR1H2ALDH1A1MMP2ANPEPNR1H3
SCHEMBL30392400 0.96 ALDH1A1 (0.44) NR1H2ALDH1A1MMP2ANPEPNR1H3
SCHEMBL26567723 0.96 ALDH1A1 (0.44) NR1H2ALDH1A1MMP2ANPEPNR1H3
SCHEMBL30571945 0.96 ALDH1A1 (0.44) NR1H2ALDH1A1MMP2ANPEPNR1H3
SCHEMBL30396157 0.94 CYP3A4 (0.43) NR1H2ALDH1A1MMP2ANPEPNR1H3
SCHEMBL6184237 0.92 ALDH1A1 (0.42) NR1H2ALDH1A1MMP2ANPEPNR1H3
SCHEMBL7629700 0.92 ALDH1A1 (0.42) NR1H2ALDH1A1MMP2ANPEPNR1H3
SCHEMBL18084464 0.90 NR1H2 (0.43) NR1H2ALDH1A1MMP2ANPEPNR1H3
SCHEMBL18109224 0.85 TP53 (0.48) NR1H2ALDH1A1MMP2ANPEPNR1H3
SCHEMBL15013224 0.84 NPC1 (0.42) NR1H2ALDH1A1NR1H3CYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240254136-A1 COMPOUNDS TARGETING RNA-BINDING PROTEINS OR RNA-MODIFYING PROTEINS Redona Therapeutics, Inc. 2024-08-01 US disclosed
EP-4114831-A1 COMPOUNDS TARGETING RNA-BINDING PROTEINS OR RNA-MODIFYING PROTEINS Twentyeight-Seven, Inc. (US) 2023-01-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240254136-A1 COMPOUNDS TARGETING RNA-BINDING PROTEINS OR RNA-MODIFYING PROTEINS NSUN3, NSUN2, RBM3 NR1H2 2354/4885ALDH1A1 3491/4885MMP2 4048/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.