Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | PRKACA | P17612 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30417443 | 1.00 | KMT2A (0.43) | KMT2ANPC1ALDH1A1KDM4EHPGD | |
| SCHEMBL29008017 | 0.80 | KMT2A (0.46) | KMT2ANPC1ALDH1A1KDM4EHPGD | |
| SCHEMBL30181185 | 0.80 | KMT2A (0.46) | KMT2ANPC1ALDH1A1KDM4EHPGD | |
| SCHEMBL30417471 | 0.80 | KMT2A (0.46) | KMT2ANPC1ALDH1A1KDM4EHPGD | |
| SCHEMBL30298033 | 0.78 | NPC1 (0.53) | KMT2ANPC1ALDH1A1KDM4EHPGD | |
| SCHEMBL30181439 | 0.78 | KMT2A (0.43) | KMT2ANPC1ALDH1A1KDM4EHPGD | |
| SCHEMBL29007756 | 0.78 | ALDH1A1 (0.50) | KMT2ANPC1ALDH1A1KDM4EHPGD | |
| SCHEMBL30954825 | 0.78 | NPC1 (0.54) | KMT2ANPC1ALDH1A1KDM4EHPGD | |
| SCHEMBL30954837 | 0.78 | NPC1 (0.52) | KMT2ANPC1ALDH1A1KDM4EHPGD | |
| SCHEMBL30297948 | 0.78 | NPC1 (0.54) | KMT2ANPC1ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4114831-A1 | COMPOUNDS TARGETING RNA-BINDING PROTEINS OR RNA-MODIFYING PROTEINS | Twentyeight-Seven, Inc. (US) | 2023-01-11 | — | — | EP | disclosed |