Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | P4HTM | Q9NXG6 | 7/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | QDPR | P09417 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24891839 | 1.00 | MAPKAPK2 (0.54) | MAPKAPK2ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL24891661 | 0.92 | MAPKAPK2 (0.52) | MAPKAPK2ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL24891932 | 0.92 | MAPKAPK2 (0.52) | MAPKAPK2ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL24670573 | 0.87 | MAPKAPK2 (0.59) | MAPKAPK2NAMPTQDPRSIGMAR1 | |
| SCHEMBL24891662 | 0.86 | MAPKAPK2 (0.47) | MAPKAPK2NAMPTQDPRSIGMAR1 | |
| SCHEMBL30182609 | 0.83 | MAPKAPK2 (0.52) | MAPKAPK2ALDH1A1KDM4ENAMPTQDPR | |
| SCHEMBL24891640 | 0.83 | MAPKAPK2 (0.52) | MAPKAPK2ALDH1A1KDM4ENAMPTQDPR | |
| SCHEMBL24891639 | 0.82 | MAPKAPK2 (0.53) | MAPKAPK2ALDH1A1NAMPTQDPRSIGMAR1 | |
| SCHEMBL24892195 | 0.82 | MAPKAPK2 (0.56) | MAPKAPK2NAMPTQDPRSIGMAR1 | |
| SCHEMBL16605556 | 0.82 | MAPKAPK2 (0.56) | MAPKAPK2NAMPTQDPRSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | disclosed |